Molecular based methods have advanced the centre testing to faster and better diagnostics. PCR methods, microarray and next generation sequencing have provided speed and
high level of accuracy. Molecular biology based methods are sensitive and quick to detect microbial pathogens in various clinical specimens.
We offer molecular detection of pathogenic viruses, bacteria and parasites from clinical specimens. MBG is ISO 15189 accredited and benefits from a stand-alone
containment Level 3 facility where samples for highly contagious pathogen are received and processed.
The Hepatitis B virus (HBV) is a member of the Hepadnaviridae with an outer lipid envelope and an icosahedral nucleocapsid core composed of protein. HBV contains a small, partially double-stranded, relaxed circular DNA genome. HBV infection is a global public health problem, with over 300 million chronically infected patients worldwide. Chronic HBV infection are associated with a high risk of developing severe liver diseases, including cirrhosis and hepatocellular carcinoma, and results in a million deaths. Symptoms of acute infection include liver inflammation, vomiting, jaundice, and abdominal pain. Modes of transmission are the same as those for the human immunodeficiency virus (HIV), but the hepatitis B virus is 50 to 100 times more infectious. Hepatitis B is usually spread when blood, semen, or another body fluid from a person infected with the Hepatitis B virus enters the body of someone who is not infected. This can happen through sexual contact with an infected person or sharing needles, syringes, or other drug-injection equipment. Hepatitis B can also be passed from an infected mother to her baby at birth.
Being able to detect and quantify the DNA allows an estimation of infectivity and the likelihood of progression to severe chronic disease. It is also useful to monitor the success of treatment. Occasionally people can be HBV DNA positive without other serological markers such as HBsAg, for example in the first two weeks of the infection. The best way to prevent Hepatitis B is by getting vaccinated.
Method
Real-Time PCR.
Sample Type
EDTA Blood, Serum.
Transport Condition
Samples should be transported at 4°C.
Turn Around Time (TAT)
TAT for routine samples is within 3 working days. Urgent Samples will be charged double and will be reported within 1-2 working days.
Samples delivered before 11:00 AM will begin processing immediately resulting in shorter TAT.
Please, contact MBG for more information
Validated
Assay Code
HPV-224
Description
HSV-1 and HSV-2 is a double stranded DNA virus. Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) are two species of human herpes viruses that replicate in the nucleus of infected cells, undergo productive infection in epithelial cells and fibroblasts, and spread to establish latent infection in sensory neurons. Latent infection is maintained for the life of an individual, from which the virus can be reactivated to cause recurrent disease. HSVs cause significant human disease, including cold sores, encephalitis, genital herpes, and corneal blindness, with HSV-2 infections increasing the likelihood of human immunodeficiency virus infection. HSV type 1 (HSV-1) is typically transmitted by oral-to-oral contact and causes infection in or around the mouth (oral herpes), but it can also cause genital herpes. HSV-2 is mainly sexually transmitted and causes genital herpes.People who already have HSV-1 are not at risk of re-infection, but they are still at risk of acquiring HSV-2. An estimated 3.7 billion people under age 50 (67%) have HSV-1 infection globally and 491 million people aged 15–49 (13%) worldwide have HSV-2 infection. Most HSV infections are asymptomatic, but symptoms of herpes include painful blisters or ulcers that can recur over time. Some medications are available to reduce the severity and frequency of symptoms, but they cannot cure the infection. The virus causes a diverse spectrum of diseases including neonatal herpes, corneal blindness, herpetic whitlow, meningitis, encephalitis, and genital herpes.
The Turnaround (TAT) for routine samples is within 3 working days.
Samples delivered after 11:00 AM will be processed next working day (unless urgent).
Urgent Samples will be reported within 24-48 hours and will be charged double.
Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. HIV has three stages: Acute HIV, Chronic stage/clinical latency and AIDS. Following initial infection an individual may not notice any symptoms, or may experience a brief period of influenza-like illness. Typically, this is followed by a prolonged incubation period with no symptoms. If the infection progresses, it interferes more with the immune system, increasing the risk of developing common infections such as tuberculosis, as well as other opportunistic infections, and tumors which are rare in people who have normal immune function. These late symptoms of infection are referred to as acquired immunodeficiency syndrome (AIDS).
There are two main types of this virus: HIV-1 and HIV-2. While both weaken the immune system, HIV-2 develops more slowly and has a lower transmission rate than HIV-1.
HIV-1 is the most common type of HIV, and it occurs all over the world. HIV-2 is mainly present in West Africa, but it is slowly starting to appear in other regions, including the United States, Europe, and India.
Though HIV-1 and HIV-2 are both retroviruses that can have similar effects on the human body, they are genetically distinct.
Pathogens Tested
HPV-222: Human immunodeficiency virus 1 (HIV-1)
HPV-223: Human immunodeficiency virus 2 (HIV-2)
Method
Real Time RT-PCR
Sample Type
Recommended specimen types: Serum or EDTA Blood(>=3mL).
Transport Condition
Sample should be transported at 4°C.
Turn Around Time (TAT)
The Turnaround (TAT) for routine samples is within 3 working days.
Samples delivered after 11:00 AM will be processed next working day (unless urgent).
Urgent Samples will be reported within 24-48 hours and will be charged double.
Molecular based methods have advanced the centre testing to faster and better diagnostics. PCR methods, microarray and next generation sequencing have provided speed and
high level of accuracy. Molecular biology based methods are sensitive and quick to detect microbial pathogens in various clinical specimens.
We offer molecular detection of pathogenic viruses, bacteria and parasites from clinical specimens. MBG is ISO 15189 accredited and benefits from a stand-alone
containment Level 3 facility where samples for highly contagious pathogen are received and processed.
The Hepatitis B virus (HBV) is a member of the Hepadnaviridae with an outer lipid envelope and an icosahedral nucleocapsid core composed of protein. HBV contains a small, partially double-stranded, relaxed circular DNA genome. HBV infection is a global public health problem, with over 300 million chronically infected patients worldwide. Chronic HBV infection are associated with a high risk of developing severe liver diseases, including cirrhosis and hepatocellular carcinoma, and results in a million deaths. Symptoms of acute infection include liver inflammation, vomiting, jaundice, and abdominal pain. Modes of transmission are the same as those for the human immunodeficiency virus (HIV), but the hepatitis B virus is 50 to 100 times more infectious. Hepatitis B is usually spread when blood, semen, or another body fluid from a person infected with the Hepatitis B virus enters the body of someone who is not infected. This can happen through sexual contact with an infected person or sharing needles, syringes, or other drug-injection equipment. Hepatitis B can also be passed from an infected mother to her baby at birth.
Being able to detect and quantify the DNA allows an estimation of infectivity and the likelihood of progression to severe chronic disease. It is also useful to monitor the success of treatment. Occasionally people can be HBV DNA positive without other serological markers such as HBsAg, for example in the first two weeks of the infection. The best way to prevent Hepatitis B is by getting vaccinated.
Method
Real-Time PCR.
Sample Type
EDTA Blood, Serum.
Transport Condition
Samples should be transported at 4°C.
Turn Around Time (TAT)
TAT for routine samples is within 3 working days. Urgent Samples will be charged double and will be reported within 1-2 working days.
Samples delivered before 11:00 AM will begin processing immediately resulting in shorter TAT.
Please, contact MBG for more information
Validated
Assay Code
HPV-224
Description
HSV-1 and HSV-2 is a double stranded DNA virus. Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) are two species of human herpes viruses that replicate in the nucleus of infected cells, undergo productive infection in epithelial cells and fibroblasts, and spread to establish latent infection in sensory neurons. Latent infection is maintained for the life of an individual, from which the virus can be reactivated to cause recurrent disease. HSVs cause significant human disease, including cold sores, encephalitis, genital herpes, and corneal blindness, with HSV-2 infections increasing the likelihood of human immunodeficiency virus infection. HSV type 1 (HSV-1) is typically transmitted by oral-to-oral contact and causes infection in or around the mouth (oral herpes), but it can also cause genital herpes. HSV-2 is mainly sexually transmitted and causes genital herpes.People who already have HSV-1 are not at risk of re-infection, but they are still at risk of acquiring HSV-2. An estimated 3.7 billion people under age 50 (67%) have HSV-1 infection globally and 491 million people aged 15–49 (13%) worldwide have HSV-2 infection. Most HSV infections are asymptomatic, but symptoms of herpes include painful blisters or ulcers that can recur over time. Some medications are available to reduce the severity and frequency of symptoms, but they cannot cure the infection. The virus causes a diverse spectrum of diseases including neonatal herpes, corneal blindness, herpetic whitlow, meningitis, encephalitis, and genital herpes.
The Turnaround (TAT) for routine samples is within 3 working days.
Samples delivered after 11:00 AM will be processed next working day (unless urgent).
Urgent Samples will be reported within 24-48 hours and will be charged double.
Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. HIV has three stages: Acute HIV, Chronic stage/clinical latency and AIDS. Following initial infection an individual may not notice any symptoms, or may experience a brief period of influenza-like illness. Typically, this is followed by a prolonged incubation period with no symptoms. If the infection progresses, it interferes more with the immune system, increasing the risk of developing common infections such as tuberculosis, as well as other opportunistic infections, and tumors which are rare in people who have normal immune function. These late symptoms of infection are referred to as acquired immunodeficiency syndrome (AIDS).
There are two main types of this virus: HIV-1 and HIV-2. While both weaken the immune system, HIV-2 develops more slowly and has a lower transmission rate than HIV-1.
HIV-1 is the most common type of HIV, and it occurs all over the world. HIV-2 is mainly present in West Africa, but it is slowly starting to appear in other regions, including the United States, Europe, and India.
Though HIV-1 and HIV-2 are both retroviruses that can have similar effects on the human body, they are genetically distinct.
Pathogens Tested
HPV-222: Human immunodeficiency virus 1 (HIV-1)
HPV-223: Human immunodeficiency virus 2 (HIV-2)
Method
Real Time RT-PCR
Sample Type
Recommended specimen types: Serum or EDTA Blood(>=3mL).
Transport Condition
Sample should be transported at 4°C.
Turn Around Time (TAT)
The Turnaround (TAT) for routine samples is within 3 working days.
Samples delivered after 11:00 AM will be processed next working day (unless urgent).
Urgent Samples will be reported within 24-48 hours and will be charged double.
